中文名 | D-Phenylalanine, N-[6-[4-(phenylmethoxy)phenyl]-4-pyrimidinyl]- |
英文名 | D-Phenylalanine, N-[6-[4-(phenylmethoxy)phenyl]-4-pyrimidinyl]- |
别名 | 化合物 T26745 |
英文别名 | BAY 73-1449 D-Phenylalanine, N-[6-[4-(phenylmethoxy)phenyl]-4-pyrimidinyl]- |
CAS | 693790-96-4 |
化学式 | C26H23N3O3 |
分子量 | 425.48 |
密度 | 1.273±0.06 g/cm3(Predicted) |
沸点 | 700.4±60.0 °C(Predicted) |
酸度系数 | 3.35±0.10(Predicted) |
体内研究 | BAY 73-1449 (0.1-1 mg/kg; i.v.) does not significantly reduce mesenteric inflow, but significantly reduces splenic shunt vessel outflow in rats. BAY 73-1449 (1-5 mg/kg, s.c. once daily for 7 d) has no effects on the degree of porto-systemic shunting in rats. BAY 73-1449 (1 mg/kg, s.c. once daily for 7 d), has no effects on portal pressures in rats. Animal Model: Male Wistar rats (250-350 g) are ligated portal vein Dosage: 0.1, 1 mg/kg Administration: A single i.v. Result: Significantly reduced shunt flow without affecting mesenteric flow. |
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